Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Is Tylenol Safe During Pregnancy? Understanding Risk Factors Seeking Health Liver injury induced by paracetamol and challenges associated with intentional and unintentional use Sex differences in glutathione metabolism and acetaminophen toxicity Potential deleterious effects of paracetamol dose regime used in Nigeria versus that of the United States of America ScienceDirect