Tylenol (acetaminophen) does not cause autism. The FDA, in its statement that there may be an association, confirmed that "a causal relationship has not been established, and studies of millions of children Acetaminophen and The Autism Connection Documenting Hope Tylenol, Autism, and Leucovorin: What Parents Need to Know. Evidence that acetaminophen triggers autism in susceptible individuals has been ignored and mishandled for more than a decade. Acetaminophen's Role in Autism and ADHD: A Mitochondrial Perspective