How to Lose Weight With PCOS The Role of l Carnitine in Mitochondria, Prevention of Metabolic Inflexibility and Disease Initiation L Carnitine has become one of the most commonly asked about supplements over the past 18 months and I can see why when looking at all the research that has come out about it over the last 2ish years., Benefits of L Carnitine for PCOS: Improve Insulin Resistance & Weight Loss The Role of Lifestyle Interventions in PCOS Management: A Systematic Review