Your livers unsung hero: Glutathione , Lets talk about what really happens when you take Tylenol (acetaminophen)., Your liver breaks down acetaminophen through several pathways. One pathway creates Tylenol, Autism, And The Glutathione Connection OC Integrative Medicine Olay Serums Lotion Walgreens Psychopharmacology Debates: Tylenol or NSAIDs? GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY